anti-CD84 antibody [CD84.1.21]

Arigo Biolaboratories

anti-CD84 antibody [CD84.1.21]

23

Functional Assay, Flow Cytometry, ImmunoPrecipitation, Other Application

Research Use Only

Monoclonal

CD84.1.21

1 mg/ml

Unconjugated

>95%

CD84

CD84 molecule

CD84 antigen (leukocyte antigen); cell surface antigen MAX.3; hCD84; hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; leukocyte differentiation antigen CD84; LY9B; mCD84; signaling lymphocytic activation molecule 5; SLAM family member 5; SLAMF5

Mouse

IgG2a

CD84 is a highly glycosylated homophilic receptor of SLAM family. It is expressed on platelets and various types of leukocytes, especially following their activation. Ligation of CD84 leads to its phosphorylation on tyrosine residues within the cytoplasmic tail. These docking sites are recognized by downstream signaling molecules, such as phosphatase SHP-2 and adaptor protein SAP/SH2D1A. The function of CD84 has not been fully elucidated yet. Although predominantly activating receptor, its modulating activity was also demonstrated.

-20°C

12352203