anti-CD86 antibody [GL-1]

Arigo Biolaboratories

anti-CD86 antibody [GL-1]

23

Functional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Other Application

Research Use Only

Monoclonal

GL-1

1 mg/ml

Unconjugated

>95%

Cd86

CD86 antigen

activation B7-2 antigen; B7; B7.2; B70; B7-2; Cd28l; Cd28l2; CLS1; early T cell costimulatory molecule-1; ETC-1; Ly5; Ly-5; Ly58; Ly-58; MB7; MB7-2; T-lymphocyte activation antigen CD86; TS/A-2

Rat

IgG2a

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

Mouse

-20°C

12352203