anti-CD89 antibody [MIP8a] (low endotoxin)
ARG22519
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetFCAR
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD89 antibody [MIP8a] (low endotoxin)
- Delivery Days Customer23
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMIP8a
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2204
- Target nameFCAR
- Target descriptionFc fragment of IgA receptor
- Target synonymsCD89; CTB-61M7.2; Fc alpha receptor; Fc fragment of IgA, receptor for; FcalphaRI; FCAR variant 14; immunoglobulin alpha Fc receptor
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203