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anti-Cellular Apoptosis Susceptibility antibody

Research Use Only
ARG55082
Arigo Biolaboratories
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Zebra Fish
TargetCSE1L
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Cellular Apoptosis Susceptibility antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1434
  • Target name
    CSE1L
  • Target description
    chromosome segregation 1 like
  • Target synonyms
    CAS; cellular apoptosis susceptibility protein; chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1-like; epididymis secretory sperm binding protein; exp2; exportin-2; importin-alpha re-exporter; XPO2
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
  • Reactivity
    Bovine, Human, Zebra Fish
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203