anti-DDR1 antibody

Arigo Biolaboratories

anti-DDR1 antibody

23

Western Blot

Research Use Only

Monoclonal

1464CT339.1.54

Unconjugated

DDR1

discoidin domain receptor tyrosine kinase 1

CAK; CD167; CD167 antigen-like family member A; cell adhesion kinase; DDR; EDDR1; epithelial discoidin domain-containing receptor 1; HGK2; mammary carcinoma kinase 10; MCK10; NEP; neuroepithelial tyrosine kinase; neurotrophic tyrosine kinase, receptor, type 4; NTRK4; protein-tyrosine kinase RTK-6; PTK3; PTK3A; PTK3A protein tyrosine kinase 3A; RTK6; TRKE; tyrosine kinase DDR; tyrosine-protein kinase CAK

Mouse

IgG2b

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Human

-20°C

12352203