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anti-Dnmt3b antibody

Research Use Only
ARG54845
Arigo Biolaboratories
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDNMT3B
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-Dnmt3b antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1789
  • Target name
    DNMT3B
  • Target description
    DNA methyltransferase 3 beta
  • Target synonyms
    DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA cytosine-5--methyltransferase 3 beta; DNA methyltransferase HsaIIIB; DNA MTase HsaIIIB; FSHD4; ICF; ICF1; M.HsaIIIB
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq, May 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203