anti-ERCC1 antibody
ARG54172
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetERCC1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-ERCC1 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Concentration18 mg/ml
- ConjugateUnconjugated
- Gene ID2067
- Target nameERCC1
- Target descriptionERCC excision repair 1, endonuclease non-catalytic subunit
- Target synonymsCOFS4; DNA excision repair protein ERCC-1; excision repair cross-complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); RAD10; UV20
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionIsoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-incision during DNA repair.Responsible,in conjunction with SLX4,for the first step in the repair of interstrand cross-links (ICL).Participates in the processing of anaphase bridge-generating DNA structures,which consist in incompletely processed DNA lesions arising during S or G2 phase,and can result in cytokinesis failure.Also required for homology-directed repair (HDR) of DNA double-strand breaks,in conjunction with SLX4.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203