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anti-ERCC1 antibody

Research Use Only
ARG54172
Arigo Biolaboratories
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetERCC1
Price on request
Packing Size
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-ERCC1 antibody
  • Delivery Days Customer
    23
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    18 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2067
  • Target name
    ERCC1
  • Target description
    ERCC excision repair 1, endonuclease non-catalytic subunit
  • Target synonyms
    COFS4; DNA excision repair protein ERCC-1; excision repair cross-complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); RAD10; UV20
  • Host
    Mouse
  • Isotype
    IgG2b
  • Scientific Description
    Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-incision during DNA repair.Responsible,in conjunction with SLX4,for the first step in the repair of interstrand cross-links (ICL).Participates in the processing of anaphase bridge-generating DNA structures,which consist in incompletely processed DNA lesions arising during S or G2 phase,and can result in cytokinesis failure.Also required for homology-directed repair (HDR) of DNA double-strand breaks,in conjunction with SLX4.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203