anti-FOXP3 (human), mAb (ANCFX2D7)

Ancell Corporation

anti-FOXP3 (human), mAb (ANCFX2D7)

10

Flow Cytometry, ELISA

Research Use Only

Monoclonal

ANCFX2D7

>95%

Mouse

IgG1

FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. - Monoclonal Antibody. Recognizes human FOXP3. Isotype: Mouse IgG1kappa. Clone: ANCFX2D7. Applications: ELISA, FACS. 50mM Sodium phosphate pH7.5, 100mM Potassium chloride, 150mM NaCl, 0.5mg/ml Gentamicin sulfate (as preservative). FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.

Human

2°C to 8°C

12352203