anti-GITRL (human), pAb

Catalog number: AG-25A-0023-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 240.00
Expected delivery time: 7 days

Product specifications for - anti-GITRL (human), pAb

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, ImmunoHistoChemistry, Western Blot
Clonality: Polyclonal
Source: Rabbit
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1mg/ml
Form supplied: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, .). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
Swiss prot ID: Q9UNG2
Safety information: 
Additional information: 
Synonyms: AG-25A-0023-C100; AdipoGen Life Sciences; Glucocorticoid-induced TNF Receptor Ligand; AITRL; Activation-inducible TNF-related Ligand; TNFSF18