anti-GITRL (human), pAb

Catalog number: AG-25A-0023-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 240.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-GITRL (human), pAb

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; ImmunoHistoChemistry; Western Blot
Species: Human
Host: Rabbit
Target: TNFSF18
Target description: TNF superfamily member 18
Source: Rabbit
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Form supplied: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Storage instructions: -20-¦C
Scientific information: 
Scientific info: GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, ..). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors. - Polyclonal Antibody. Recognizes human GITRL. Detects a band of ~15-17kDa by Western blot. Does not cross-react with mouse GITRL. Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. GITRL is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis, .). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T-cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.
Gene ID: 8995
Swiss prot ID: Q9UNG2
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: activation-inducible TNF-related ligand; AITR ligand; AITRL; GITR ligand; GITRL; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; hGITRL; TL6; TNLG2A; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand 2A; tumor necrosis factor ligand superfamily member 18; tumor necrosis factor superfamily member 18