anti-GLUD1 + GLUD2 antibody

Arigo Biolaboratories

anti-GLUD1 + GLUD2 antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

GLUD1

glutamate dehydrogenase 1

epididymis secretory sperm binding protein; epididymis tissue sperm binding protein Li 18mP; GDH; GDH1; GLUD; glutamate dehydrogenase (NAD(P)+); glutamate dehydrogenase 1, mitochondrial

Goat

IgG

This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009]

Bovine, Canine, Human

-20°C

12352203