anti-H Cadherin antibody
ARG55232
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCDH13
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-H Cadherin antibody
- Delivery Days Customer23
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1012
- Target nameCDH13
- Target descriptioncadherin 13
- Target synonymscadherin 13, H-cadherin (heart); cadherin-13; CDHH; H-cadherin (heart); heart cadherin; P105; T-cad; T-cadherin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203