anti-HLA DR antibody [YE2/36-HLK]
ARG22787
ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetHLA-DRA
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-HLA DR antibody [YE2/36-HLK]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDYE2/36-HLK
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3122
- Target nameHLA-DRA
- Target descriptionmajor histocompatibility complex, class II, DR alpha
- Target synonymshistocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain; HLA-DRA1; MHC class II antigen DRA
- HostRat
- IsotypeIgG2a
- Scientific DescriptionHLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203