anti-IA2 antibody

Arigo Biolaboratories

anti-IA2 antibody

23

Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PTPRN

protein tyrosine phosphatase receptor type N

IA2; IA-2; IA-2/PTP; ICA 512; ICA512; insulinoma-associated tyrosine-phosphatase-like protein; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase-like N; PTP IA-2; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N

Goat

IgG

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]

Human, Rat

-20°C

12352203