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anti-IL10 antibody [JES5-16E3] (Biotin)

Research Use Only
ARG21480
Arigo Biolaboratories
ApplicationsFlow Cytometry, ImmunoFluorescence, ELISA, ELISpot Assay, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetIl10
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-IL10 antibody [JES5-16E3] (Biotin)
  • Delivery Days Customer
    23
  • Applications
    Flow Cytometry, ImmunoFluorescence, ELISA, ELISpot Assay, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JES5-16E3
  • Concentration
    0.5 mg/ml
  • Conjugate
    Biotin
  • Gene ID16153
  • Target name
    Il10
  • Target description
    interleukin 10
  • Target synonyms
    CSIF; cytokine synthesis inhibitory factor; If2a; IL-; Il-10; interferon 2a; interleukin-10
  • Host
    Rat
  • Isotype
    IgG2b
  • Scientific Description
    The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203