anti-CD107a / LAMP1 antibody [H4A3] (azide free)

Arigo Biolaboratories

anti-CD107a / LAMP1 antibody [H4A3] (azide free)

23

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

H4A3

0.1 mg/ml

Unconjugated

>95%

LAMP1

lysosomal associated membrane protein 1

CD107 antigen-like family member A; CD107a; LAMP-1; LAMPA; LGP120; lysosome-associated membrane glycoprotein 1; lysosome-associated membrane protein 1

Mouse

IgG1

CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

Human

-20°C

12352203