anti-MDA5 (human), mAb (Hely-1)

Catalog number: AG-20B-0013-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 380.00
Expected delivery time: 7 days

Product specifications for - anti-MDA5 (human), mAb (Hely-1)

Product group: Antibodies
Category: Primary Antibodies
Application: ELISA, ImmunoPrecipitation, Western Blot
Clonality: Monoclonal
Isotype: IgG1
Source: Purified from concentrated hybridoma tissue culture supernatant.
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1mg/ml
Form supplied: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5 -ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
Clone ID: Hely-1
Swiss prot ID: Q9BYX4
Safety information: 
Additional information: 
Synonyms: AG-20B-0013-C100; AdipoGen Life Sciences; Helicard; Melanoma Differentiation-associated Gene 5