anti-NF2 / Merlin phospho (Ser518) antibody

Arigo Biolaboratories

anti-NF2 / Merlin phospho (Ser518) antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NF2

neurofibromin 2

ACN; BANF; bilateral acoustic neurofibromatosis; merlin; merlin-1; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromin 2 (bilateral acoustic neuroma); SCH; schwannomerlin; schwannomin

Rabbit

IgG

Phosphorylated

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity.

Human

-20°C

12352203