anti-NAIP1/2/5 (mouse), mAb (Naipa-1)

Catalog number: AG-20B-0045-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 360.00
Expected delivery time: 7 days

Product specifications for - anti-NAIP1/2/5 (mouse), mAb (Naipa-1)

Product group: Antibodies
Category: Primary Antibodies
Application: Western Blot
Clonality: Monoclonal
Isotype: IgG2b Kappa
Source: Purified from concentrated hybridoma tissue culture supernatant.
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1mg/ml
Form supplied: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to caspase-1 activation. The NLR member IPAF/NLRC4 senses bacterial flagellin and a conserved type III secretion system (TTSS) rod component. A member of the NLR family, NAIP5 directly and specifically interacts with flagellin, triggers a physical NAIP5-NLRC4 association leading to NLRC4 activation. The related NAIP2 functions analogously to NAIP5, serving as a specific inflammasome receptor for TTSS rod proteins such as Salmonella PrgJ and Burkholderia BsaK.
Clone ID: Naipa-1
Swiss prot ID: Q9R016
Safety information: 
Additional information: 
Synonyms: AG-20B-0045-C100; AdipoGen Life Sciences; Neuronal Apoptosis Inhibitory Protein 1, 2, 5; Baculoviral IAP Repeat-containing Protein 1a, 1b, 1e; Birc 1a, 1b, 1e