anti-Neuropeptide Y antibody
ARG57559
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetNPY
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Neuropeptide Y antibody
- Delivery Days Customer23
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID4852
- Target nameNPY
- Target descriptionneuropeptide Y
- Target synonymsprepro-neuropeptide Y; pro-neuropeptide Y; PYY4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203