Catalog number: HPA003097
Brand: Atlas Antibodies
Packing: 100 ul
Other sizes: 25 ul, please contact us.
Price: € 333.00
Expected delivery time: 7 days
Immunohistochemical staining of hum...
Western blot analysis in U2OS cells...
Immunohistochemical staining of hum...
Immunofluorescent staining of human...
Immunohistochemical staining of hum...
Western blot analysis in mouse cell...
Immunohistochemical staining of hum...

Product specifications for - Anti-NF2

Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoCytoChemistry; ImmunoFluorescence; ImmunoHistoChemistry; Western Blot
Species: Human, Mouse, Rat
Host: Rabbit
Target: NF2
Target description: neurofibromin 2
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage instructions: Store at +4-¦C for short term storage. Long time storage is recommended at -20-¦C.
Scientific information: 
Scientific info: Specification: This antibody has been used for staining of 48 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type.
Gene ID: 4771
Swiss prot ID: P35240
Related products: 
Related products: Corresponding Atlas Antigen: APrEST73592
Additional information: 
Synonyms: ACN; BANF; merlin; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromin 2 (bilateral acoustic neuroma); Neurofibromin-2; SCH; schwannomerlin; schwannomin
Zhang N, Bai H, David KK, Dong J, Zheng Y, Cai J, Giovannini M, Liu P, Anders RA, Pan D. "The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals". Dev Cell 2010 Jul 20; 19(1):27-38. DOI: 10.1016/j.devcel.2010.06.015. Read more
Lavado A, He Y, Paré J, Neale G, Olson EN, Giovannini M, Cao X. "Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators". Development 2013 Aug; 140(16):3323-3334. DOI: 10.1242/dev.096537. Read more
Chen Q, Zhang N, Xie R, Wang W, Cai J, Choi KS, David KK, Huang B, Yabuta N, Nojima H, Anders RA, Pan D. "Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP". Genes Dev 2015 Jun 15; 29(12):1285-1297. DOI: 10.1101/gad.264234.115. Read more
Serinagaoglu Y, Paré J, Giovannini M, Cao X. "Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development". Dev Biol 2015/02/01; 398(1):97-109. Epub 2014 Nov 26. DOI: 10.1016/j.ydbio.2014.11.017. Read more
Reginensi A, Enderle L, Gregorieff A, Johnson RL, Wrana JL, McNeill H. "A critical role for NF2 and the Hippo pathway in branching morphogenesis". Nat Commun 2016 Aug 2; 7:12309. Epub 2016 Aug 2. DOI: 10.1038/ncomms12309. Read more