anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)

Catalog number: AG-20B-0006-C100
Brand: AdipoGen Life Sciences
Packing: 100 ug
Price: € 390.00
Expected delivery time: 7 days
Quantity:

Product specifications for - anti-NLRP3/NALP3 (mouse), mAb (Cryo-1)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: Western Blot
Species: Mouse
Target: Nlrp3
Target description: NLR family, pyrin domain containing 3
Isotype: IgG2b
Source: Purified from concentrated hybridoma tissue culture supernatant.
Properties: 
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Form supplied: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Storage instructions: -20°C
Scientific information: 
Scientific info: Monoclonal Antibody. Recognizes mouse NLRP3/NALP3. Isotype: Mouse IgG2b. Clone: Cryo-1. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA). - The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).
Clone ID: Cryo-1
Gene ID: 216799
Swiss prot ID: Q8R4B8
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: AGTAVPRL; AII/AVP; Cias1; cold autoinflammatory syndrome 1 protein homolog; cryopyrin; FCAS; FCU; mast cell maturation-associated-inducible protein 1; Mmig1; MWS; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; Pypaf1; PYRIN-containing APAF1-like protein 1
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes: E. Ydens, et al.; J. Neuroinfl. 12, 143 (2015) Read more