anti-NMDAR1 C2 antibody
ARG52355
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Human, Rat
TargetGrin1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-NMDAR1 C2 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID24408
- Target nameGrin1
- Target descriptionglutamate ionotropic receptor NMDA type subunit 1
- Target synonymsGluN1; glutamate [NMDA] receptor subunit zeta-1; glutamate receptor ionotropic, NMDA 1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; neurotransmitter receptor; NMDA R1 receptor C1 cassette; NMDAR1; NMD-R1; N-methyl-D-aspartate glutamate receptor; N-methyl-D-aspartate receptor subunit NR1; NR1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimers, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). Increased membrane surface expression of the NMDAR, NR1-Subunit has been associated with synaptic plasticity (Grosshans et al., 2002). There are a number of different splice variants of the NR1-Subunit (Foldes et al., 1994; Zukin and Bennett, 1995). Differential splicing of three exons in the NR1-Subunit generates up to eight NR1-Subunit splice variants and 7 of these have been identified in cDNA libraries. These exons encode a 21 amino acid N-terminal domain (N1) and adjacent sequences in the C-terminus (C1 and C2). Splicing out the C2 cassette eliminates the first stop codon and produces a new reading frame that generates a new sequence of 22 amino acids (C2). Considerable attention has been focused on the distribution and exp
- ReactivityBovine, Human, Rat
- Storage Instruction-20°C
- UNSPSC12352203