anti-Notch1 (mouse), mAb (22E5)

AdipoGen Life Sciences

anti-Notch1 (mouse), mAb (22E5)

10

Flow Cytometry

Research Use Only

Monoclonal

22E5

1 mg/ml

>95%

Notch1

notch 1

9930111A19Rik; lin; lin-12; major type A protein; Mi; Mis6; Motch A; mT14; N; N1; neurogenic locus notch homolog protein 1; Notch gene homolog 1; p300; Ta; Tan1

Rat

IgG2a

Monoclonal Antibody. Recognizes endogenous mouse Notch-1 receptor. Isotype: Rat IgG2akappa. Clone: 2.20E+06. Applications: FACS. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins. - Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

Mouse

2°C to 8°C,-20°C

12352203