anti-PCNA antibody [PC10] (PE)

Arigo Biolaboratories

anti-PCNA antibody [PC10] (PE)

23

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PC10

RPE

Pcna

proliferating cell nuclear antigen

cyclin; Pcna/cyclin; PCNAR; proliferating cell nuclear antigen

Mouse

IgG2a

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Rat

2°C to 8°C

12352203