anti-PDE11A antibody

Arigo Biolaboratories

anti-PDE11A antibody

23

Dot Blot, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

PDE11A

phosphodiesterase 11A

cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; PPNAD2

Rabbit

IgG

The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203