Anti-Phosphotyrosine Antibody, clone 4G10 , agarose conjugate

Catalog number: 16-101
Brand: Merck (Millipore)
Packing: 1 mg
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Price: € 1280.00
Expected delivery time: 7 days
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Product specifications for - Anti-Phosphotyrosine Antibody, clone 4G10 , agarose conjugate

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Product group: Antibodies
Category: Primary Antibodies
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Application note: This product is useful for immunoprecipitation and immunoaffinity chromatography methods.Suitable for immunoprecipitation and affinity purification.
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Host: MO
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Clonality: Monoclonal
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  Research Use Only
UNSPSC: 12352203
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Storage instructions: Stable for 1 year at 2-8°C from date of receipt.
Scientific information: 
Scientific info: Some of the tyrosine residues can be tagged with a phosphate group (phosphorylated) by protein kinases. (In its phosphorylated state, it is referred to as phosphotyrosine). Tyrosine phosphorylation is considered as one of the key steps in signal transduction and regulation of enzymatic activity. The advent of anti-phospho-tyrosine antibodies is one of significant events in signal transduction research. Before the availability of anti-phosphotyrosine antibodies, tyrosyl phospyhorylation of proteins and enzymes was investigated through hazardous and time-consuming radioactive experiments. Anti-phosphotyrosine antibodies are commonly used in western blots after the targeted proteins have been immunoprecipitated to measure the tyrosyl phosphorylation of the proteins. Anti-phosphotyrosine antibodies are also directly used on cell lysate to examine the overall change of tyrosine phosphorylation level in reponse to various treatments.
Clone ID: 4G10
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Synonyms: 16-101; Merck; Millipore