anti-PKC zeta phospho (Thr560) antibody
ARG57610
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPRKCZ
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-PKC zeta phospho (Thr560) antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5590
- Target namePRKCZ
- Target descriptionprotein kinase C zeta
- Target synonymsnPKC-zeta; PKC2; PKC-ZETA; protein kinase C zeta type
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionProtein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203