anti-PKR phospho (Thr451) antibody
ARG51769
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetEIF2AK2
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-PKR phospho (Thr451) antibody
- Delivery Days Customer23
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5610
- Target nameEIF2AK2
- Target descriptioneukaryotic translation initiation factor 2 alpha kinase 2
- Target synonymsdouble stranded RNA activated protein kinase; eIF-2A protein kinase 2; EIF2AK1; interferon-induced, double-stranded RNA-activated protein kinase; interferon-inducible elF2alpha kinase; LEUDEN; P1/eIF-2A protein kinase; p68 kinase; PKR; PPP1R83; PRKR; protein kinase R; protein kinase, interferon-inducible double stranded RNA dependent; protein phosphatase 1, regulatory subunit 83; tyrosine-protein kinase EIF2AK2
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionFollowing activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203