anti-PLA2G4A antibody
ARG65251
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetPLA2G4A
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-PLA2G4A antibody
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID5321
- Target namePLA2G4A
- Target descriptionphospholipase A2 group IVA
- Target synonymscalcium-dependent phospholipid-binding protein; cPLA2; cPLA2-alpha; cytosolic phospholipase A2; GURDP; lysophospholipase; phosphatidylcholine 2-acylhydrolase; phospholipase A2, group IVA (cytosolic, calcium-dependent); PLA2G4
- HostGoat
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Rat
- Storage Instruction-20°C
- UNSPSC12352203