anti-BLNK / SLP65 antibody

Arigo Biolaboratories

anti-BLNK / SLP65 antibody

23

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

>95%

BLNK

B cell linker

AGM4; B cell adaptor containing SH2 domain; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; BLNK-S; cytoplasmic adapter protein; LY57; SLP65; SLP-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa

Rabbit

IgG

SLP65 / BLNK (SH2 domain-containing leukocyte-specific phosphoprotein of 65 kDa; B cell linker protein), also known as BASH, is an adaptor protein that plays key role in B cell activation initiated by cross-linking the B cell receptor (BCR). Phosphorylated by Syk tyrosine kinase, SLP65 serves as a scaffold for Btk tyrosine kinase, Vav1 guanine nucleotide exchange factor, phospholipase C gamma2, as well as Grb2 and Nck adaptor proteins; thus represents a central linker protein that bridges the BCR-associated kinases with a multitude of signaling pathways.

Human

-20°C

12352203