anti-SPHK1 antibody

Arigo Biolaboratories

anti-SPHK1 antibody

23

ImmunoPrecipitation, Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

SPHK1

sphingosine kinase 1

acetyltransferase SPHK1; SK 1; sphingosine kinase 1; SPHK; SPK 1

Goat

IgG

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Bovine, Canine, Human, Mouse, Rat

-20°C

12352203