anti-STIM1 antibody [CDN3H4]
ARG63104
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetSTIM1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-STIM1 antibody [CDN3H4]
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCDN3H4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Estimated Purity>95%
- Gene ID6786
- Target nameSTIM1
- Target descriptionstromal interaction molecule 1
- Target synonymsD11S4896E; GOK; IMD10; STRMK; stromal interaction molecule 1; TAM; TAM1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionSTIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
- Storage Instruction-20°C
- UNSPSC12352203