anti-Syntaxin antibody [SP8]

Arigo Biolaboratories

anti-Syntaxin antibody [SP8]

23

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

SP8

Unconjugated

STX1A

syntaxin 1A

HPC-1; neuron-specific antigen HPC-1; P35-1; STX1; SYN1A; syntaxin 1A (brain); syntaxin-1A

Mouse

IgG1

Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010).

Human

-20°C

12352203