anti-TDP43 antibody
ARG64788
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Human, Mouse, Porcine, Rat
TargetTARDBP
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-TDP43 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- ConjugateUnconjugated
- Gene ID23435
- Target nameTARDBP
- Target descriptionTAR DNA binding protein
- Target synonymsALS10; TAR DNA-binding protein 43; TAR DNA-binding protein-43; TDP-43
- HostGoat
- IsotypeIgG
- Scientific DescriptionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Canine, Human, Mouse, Porcine, Rat
- Storage Instruction-20°C
- UNSPSC12352203