anti-TRAM (human), pAb (AL239)

AdipoGen Life Sciences

anti-TRAM (human), pAb (AL239)

10

Western Blot

Research Use Only

Polyclonal

TICAM2

toll like receptor adaptor molecule 2

cytoplasmic adaptor; MyD88-4; NF-kappa-B-activating protein 502; putative NF-kappa-B-activating protein 502; TICAM-2; TIR domain-containing adapter molecule 2; TIRAP3; TIRP; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; toll-like receptor adaptor protein 3; TRAM; TRIF-related adaptor molecule

Rabbit

Polyclonal Antibody. Recognizes human TRAM. Source: Rabbit. Applications: WB. Liquid. Neat serum containing 0.02% sodium azide. TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas. - TRAM functions in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. It is also involved in IL-1-triggered NF-kappaB activation, functioning upstream of IRAK1, IRAK2, TRAF6 and IKBKB. TRAM physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TRL4 signal to TICAM-1. It is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle and pancreas.

Human

2°C to 8°C,-20°C

12352203