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GTX116009 ICC/IF Image
GTX116009 ICC/IF Image
GTX116009 ICC/IF Image

APC antibody [C3], C-term

Research Use Only
GTX116009
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    APC antibody [C3], C-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.44 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. Yamaguchi S et al., 2018 Feb 13, Oncotarget
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  • Sex chromosome complement influences functional callosal myelination. Moore S et al., 2013 Aug 15, Neuroscience
    Read more