APOBEC3 gamma antibody, PAb
ORB67157
Overview
- SupplierBiorbyt
- Product NameAPOBEC3 gamma antibody, PAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:500-1:1000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit polyclonal to APOBEC3 gamma.DNA dC-dU-editing enzyme APOBEC-3G (APOBEC3G) belongs to the cytidine and deoxycytidylatedeaminase family. It is a DNA deaminase (cytidine deaminase) that mediates a form of innateresistance to retroviral infections (at least to HIV-1 infection) by triggering G-to-A hypermutation in thenewly synthesized viral DNA. The inhibition of viral replication is either due to the degradation of theminus strand before its integration or to the lethality of the hypermutations. APOBEC3G also inhibitsthe infectivity of retroviral particles only distantly related to HIV-1, such as the simianimmunodeficiency virus (SIV), the equine infectious anemia virus (EIAV) and the murine leukemiavirus (MLV).
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203