APOL1 Antibody, Rabbit PAb

Catalog number: HPA018885
Brand: Atlas Antibodies
Packing: 100 ul
Price: € 327.00
Expected delivery time: 7 days
Quantity:

Product specifications for - APOL1 Antibody, Rabbit PAb

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoHistoChemistry, Western Blot
Host: Rabbit
Target: APOL1
Target description: apolipoprotein L, 1
Clonality: Polyclonal
Isotype: IgG
Properties: 
Purity: Purification method: Affinity purified using the PrEST antigen as affinity ligand
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage instructions: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Scientific information: 
Scientific info: Specification: This antibody has been used for staining of 48 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type.
Gene ID: 8542
Swiss prot ID: O14791
Related products: 
Related products: Corresponding Atlas Antigen: APrEST84510
Additional information: 
Synonyms: HPA018885; APOL1 / Apolipoprotein L; APOL1; FSGS4; APOL-I; APOL; APO-L; apolipoprotein L1; apolipoprotein L, 1
Madhavan SM, O'Toole JF, Konieczkowski M, Ganesan S, Bruggeman LA, Sedor JR. "APOL1 Localization in Normal Kidney and Nondiabetic Kidney Disease". J Am Soc Nephrol 2011 Nov; 22(11):2119-2128. DOI: 10.1681/ASN.2011010069. Read more
Johnstone DB, Shegokar V, Nihalani D, Rathore YS, Mallik L, Ashish, Zare V, Ikizler HO, Powar R, Holzman LB. "APOL1 Null Alleles from a Rural Village in India Do Not Correlate with Glomerulosclerosis". PLoS One 2012; 7(12):e51546. Epub 2012 Dec 26. DOI: 10.1371/journal.pone.0051546. Read more
Ma L, Shelness GS, Snipes JA, Murea M, Antinozzi PA, Cheng D, Saleem MA, Satchell SC, Banas B, Mathieson PW, Kretzler M, Hemal AK, Rudel LL, Petrovic S, Weckerle A, Pollak MR, Ross MD, Parks JS, Freedman BI. "Localization of APOL1 Protein and mRNA in the Human Kidney: Nondiseased Tissue, Primary Cells, and Immortalized Cell Lines". J Am Soc Nephrol 2014 Jul 10; 26(2):339-348. Epub 2014 Jul 10. DOI: 10.1681/ASN.2013091017. Read more
Khatua AK, Cheatham AM, Kruzel ED, Singhal PC, Skorecki K, Popik W. "Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1". Am J Physiol Cell Physiol 2015 Apr 29; 309(1):C22-C37. Epub 2015 Apr 29. DOI: 10.1152/ajpcell.00384.2014. Read more
Cheng D, Weckerle A, Yu Y, Ma L, Zhu X, Murea M, Freedman BI, Parks JS, Shelness GS. "Biogenesis and cytotoxicity of APOL1 renal risk variant proteins in hepatocytes and hepatoma cells". J Lipid Res 2015 Aug; 56(8):1583-1593. DOI: 10.1194/jlr.M059733. Read more
Madhavan SM, O’Toole JF, Konieczkowski M, Barisoni L, Thomas DB, Ganesan S, Bruggeman LA, Buck M, Sedor JR. "APOL1 variants change C-terminal conformational dynamics and binding to SNARE protein VAMP8". JCI Insight 2017 Jul 20; 2(14):e92581. Epub 2017 Jul 20. DOI: 10.1172/jci.insight.92581. Read more