GTX100053 WB Image
GTX100053 WB Image
Apolipoprotein E antibody [C2C3], C-term
GTX100053
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameApolipoprotein E antibody [C2C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.66 mg/ml
- IsotypeIgG
- Scientific DescriptionChylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A Protein Corona Adsorbed to a Bacterial Magnetosome Affects Its Cellular Uptake. Lai W et al., 2020, Int J NanomedicineRead more
- Increased expression of ApoE and protection from amyloid-beta toxicity in transmitochondrial cybrids with haplogroup K mtDNA. Thaker K et al., 2016 Sep, Neurobiol DisRead more
- Proteomic Profiling Reveals the Architecture of Granulomatous Lesions Caused by Tuberculosis and Mycobacterium avium Complex Lung Disease. Seto S et al., 2019, Front MicrobiolRead more