APRIL antibody [Aprily-1]
GTX16088
Overview
- SupplierGeneTex
- Product NameAPRIL antibody [Aprily-1]
- Delivery Days Customer10
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAprily-1
- HostMouse
- IsotypeIgG
- Scientific DescriptionMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203