GTX40848 WB Image
Asparaginase antibody (HRP)
GTX40848
Overview
- SupplierGeneTex
- Product NameAsparaginase antibody (HRP)
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration10 mg/ml
- ConjugateHRP
- HostRabbit
- IsotypeIgG
- Scientific DescriptionAsparaginase is an enzyme purified from E. coli and Erwinia carotovora. It acts by deaminating extracellular L asparagine, an amino acid that appears to be essential for protein synthesis by some tumour cells which are unable to synthesise asparagine. Asparaginase from Erwinia carotovora is serologically and biochemically distinct from asparaginase from E. coli, although its antineoplastic activity and toxicity is similar. Asparaginase is usually considered to be cell cycle phase nonspecific, but it may block some cells in G1 or S phase. Asparaginase reduces cellular and humoral immunity.E.coli contains two L asparaginase isoenzymes: L asparaginase I, a low affinity enzyme located in the cytoplasm, and L asparaginase II, a high affinity secreted enzyme.
- ReactivityBacteria
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- An urchin-like helical polypeptide-asparaginase conjugate with mitigated immunogenicity. Hu Y et al., 2021 Jan, BiomaterialsRead more