GTX113389 ICC/IF Image
GTX113389 ICC/IF Image
Aspartoacylase antibody [N1C3-2]
GTX113389
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameAspartoacylase antibody [N1C3-2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.33 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Ex vivo MR microscopy of a human brain with multiple sclerosis: Visualizing individual cells in tissue using intrinsic iron. Nair G et al., 2020 Dec, NeuroimageRead more
- Expression of aspartoacylase (ASPA) and Canavan disease. Sommer A et al., 2012 Sep 1, GeneRead more
- Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. Gautier EL et al., 2014 Jul 28, J Exp MedRead more
- GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation. Choi BR et al., 2020 May 5, Cell RepRead more
- N-acetylaspartate (NAA) and N-acetylaspartylglutamate (NAAG) promote growth and inhibit differentiation of glioma stem-like cells. Long PM et al., 2013 Sep 6, J Biol ChemRead more
- N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes. Huber K et al., 2019 Mar, Biochim Biophys Acta Mol Cell ResRead more
- Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility. Larson VA et al., 2018 Mar 29, ElifeRead more
- Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase. Xin W et al., 2019 May 21, Cell RepRead more
- Prenatal overexpression of platelet-derived growth factor receptor A results in central nervous system hypomyelination. Cardona HJ et al., 2021 Oct, Brain BehavRead more
- Remyelination alters the pattern of myelin in the cerebral cortex. Orthmann-Murphy J et al., 2020 May 27, ElifeRead more