GTX115032 ICC/IF Image
GTX115032 ICC/IF Image
Ataxin 3 antibody
GTX115032
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameAtaxin 3 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.36 mg/ml
- IsotypeIgG
- Scientific DescriptionMachado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is the cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Amniotic fluid proteome analysis from Down syndrome pregnancies for biomarker discovery. Cho CK et al., 2010 Jul 2, J Proteome ResRead more
- Ataxin-3 expression correlates with the clinicopathologic features of gastric cancer. Zeng LX et al., 2014, Int J Clin Exp MedRead more
- The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models. Hsu JY et al., 2017, Front Mol NeurosciRead more