Overview
- SupplierGeneTex
- Product NameATG12 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.36 mg/ml
- IsotypeIgG
- Scientific DescriptionAutophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Wei RJ et al., 2016 Nov 15, Toxicol Appl PharmacolRead more
- Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Liu YH et al., 2017 Jan 30, Sci RepRead more
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells. Lin TY et al., 2020 Jul, AutophagyRead more
- Chloramphenicol Induces Autophagy and Inhibits the Hypoxia Inducible Factor-1 Alpha Pathway in Non-Small Cell Lung Cancer Cells. Hsu HL et al., 2019 Jan 3, Int J Mol SciRead more
- Fisetin Protects PC12 Cells from Tunicamycin-Mediated Cell Death via Reactive Oxygen Species Scavenging and Modulation of Nrf2-Driven Gene Expression, SIRT1 and MAPK Signaling in PC12 Cells. Yen JH et al., 2017 Apr 17, Int J Mol SciRead more
- Helicobacter pylori cholesterol glucosylation modulates autophagy for increasing intracellular survival in macrophages. Lai CH et al., 2018 Dec, Cell MicrobiolRead more
- In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells. Chen JC et al., 2019 Sep 9, BiomoleculesRead more
- Inhibition of Avian Influenza A Virus Replication in Human Cells by Host Restriction Factor TUFM Is Correlated with Autophagy. Kuo SM et al., 2017 Jun 13, MBioRead more
- miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity. Koh EH et al., 2018 Dec, DiabetesRead more