ATG7 antibody, PAb
ORB178707
ApplicationsWestern Blot
Product group Antibodies
ReactivityChicken, Human, Mouse, Rat
Overview
- SupplierBiorbyt
- Product NameATG7 antibody, PAb
- Delivery Days Customer10
- ApplicationsWestern Blot
- Applications SupplierWestern blot - 0.1-0.5 μg/ml - Human, Rat - Mouse - WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration500 ug/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionAutophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.
- ReactivityChicken, Human, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203