ATXN3 antibody, PAb

Biorbyt

ATXN3 antibody, PAb

10

Western Blot

WB: 1:250-1:2000 WB

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Goat

IgG

Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.

All Species, Chicken, Equine, Feline, Hamster, Human, Mouse, Rabbit, Rat, Sheep

12352203