GTX85607 WB Image
GTX85607 WB Image
Aurora B (phospho Thr232) antibody
GTX85607
ApplicationsDot Blot, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey
Overview
- SupplierGeneTex
- Product NameAurora B (phospho Thr232) antibody
- Delivery Days Customer10
- ApplicationsDot Blot, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionChromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM]
- ReactivityHuman, Monkey
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Bioisosteric replacement of an acylureido moiety attached to an indolin-2-one scaffold with a malonamido or a 2/4-pyridinoylamido moiety produces a selectively potent Aurora-B inhibitor. Wang HC et al., 2014 Sep 12, Eur J Med ChemRead more
- Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia. Jagtap AD et al., 2014 Oct 6, Eur J Med ChemRead more