GTX113951 IHC-P Image
GTX113951 IHC-P Image
BACE2 antibody [C1C3]
GTX113951
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameBACE2 antibody [C1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.83 mg/ml
- IsotypeIgG
- Scientific DescriptionCerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimers disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the Down critical region of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Protection against the Neurotoxic Effects of beta-Amyloid Peptide on Cultured Neuronal Cells by Lovastatin Involves Elevated Expression of alpha7 Nicotinic Acetylcholine Receptors and Activating Phosphorylation of Protein Kinases. Zhao L et al., 2018 Apr, Am J PatholRead more