BAK antibody [N1N2], N-term

Catalog number: GTX100063_100ul
Brand: GeneTex
Packing: 100 ul
Other sizes: 25 ul
Price: € 334.00
Expected delivery time: 10 days
GTX100063 IHC-P Image
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GTX100063 WB Image
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Product specifications for - BAK antibody [N1N2], N-term

Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoHistoChemistry; ImmunoHistoChemistry Parrafin; Western Blot
Host: Rabbit
Target: BAK1
Target description: BCL2 antagonist/killer 1
Clonality: Polyclonal
Isotype: IgG
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Scientific information: 
Scientific info: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq]
Gene ID: 578
Swiss prot ID: Q16611
Additional information: 
Synonyms: apoptosis regulator BAK; BAK; BAK-LIKE; bcl-2 homologous antagonist/killer; bcl2-L-7; BCL2L7; BCL2-like 7 protein; bcl-2-like protein 7; CDN1; pro-apoptotic protein BAK
"Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species." Lee CW et al., 2019 Aug, J Cell Physiol Read more
"Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells." Lin MH et al., 2014 Jul 25, Chem Biol Interact Read more
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"The miR-204-3p-targeted IGFBP2 pathway is involved in xanthohumol-induced glioma cell apoptotic death." Chen PH et al., 2016 Nov, Neuropharmacology Read more