Bassoon antibody, PAb (RPE)

Biorbyt

Bassoon antibody, PAb (RPE)

10

Western Blot, ImmunoHistoChemistry

WB (1:1000), IHC (1:400) WB, IHC

Research Use Only

Polyclonal

1 mg/ml

RPE

Rabbit

Rabbit polyclonal to Bassoon (RPE). Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors..

Human, Mouse, Rat

2°C to 8°C

12352203